Saturday, November 12, 2011

Macronutrient Needs In Cancer Patients

When nutrition is required for long-term or there is difficulty fitting the hose can be done in surgical or endoscopic with esofagostomi, gastrostomi or jejonostomi. Speed ​​of enteral nutrition depends on the condition of patients. Patients with cancers of the head where the neck is still gut can be given well a bolus 300-500 cc several times per day, post-gastrectomy patients require administration by drip slowly 200 cc / hour, people with short bowel, malabsorption, radiation induced enteritis 100 cc / hour.

Food ingredients for enteral nutrition can be provided with nutritional counseling, may also use the enteral nutrition formula had circulated on the market that in general there are two categories based on the content of karohidrat that is full of fat and protein digestion and partial digestion formula formula. There are preparations are also high in protein or contain substances that are needed for improved its Immunological status of patients.

Parenteral nutrition (NPE) is given to sufficient sources of essential nutrients without the use of the gastrointestinal tract of intravenously. NPE can be divided into partial NPE (NPE-P) and total NPE (NPE-T) through peripheral or central vein. Tumors that affect the digestive system or actions which involving the digestive system resulting in impaired ingestion and digestion an indication of NPE. In granting the NPE consider types of solutions are required in accordance with the needs of macro-and micronutrients, note osmolarity of the solution (preferably less than 800-1000 mOsm / l and when it is not possible can be done infusion branch).

Needs macronutrient (carbohydrates fats and proteins) of cancer patients is very individual several studies have shown that about 50-60% of cancer patients who are treated feel abnormalities expenditur resting energy (REE) are highly variable so it is difficult to determine caloric needs in general. to determine the need for calories, should be set in advance the goal of nutritional therapy and determine the factors that influence it such as nutritional status, type of tumor, therapy should be given to the tumor, presence of infection and disease duration. Calorie needs for maintenance purposes is 115-130% of REE, while uintuk increase BB is required to 150% REE. Measurement of REE based on Harnis Benedict formula: for men REE (kcal / day) = 666 + (13.7 x weight) + (5 x TB) - (6.8 x age); women REE (kcal / day) = 655 + (9.5 x weight) + (1.8 x TB) - (4.7 x age). BB is weight in kilograms, TB is high bdan in cm, age in years. Patients can be added around 20-50% of REE are given in the form non-protein calories to fulfill energy during activity or in connection expenditur with illness. Energy needs can also be estimated by multiplying as follows: BB x 30-35 kcal / day. Protein requirement is 0.8 to 1.2 grams per kg BB per day. Patients with malnutrition can be given 1.5 g / kg BW / day. Required polyunsaturated fatty acids (linoleic acid) of about 2-4% of total calories and cholesterol <200 mg / day.

Mikronitrien consists of vitamins, minerals and elements frace. several studies have showed that deficiency of certain vitamins, minerals and elements related frace with certain cancers. Prompts consumption of vitamins are: Vitamin C 300 - 400 mg / day but some researchers recommend vitamin C intake of 300-1000 mg reduce the risk of cancer, Vitamin A (β - carotene) as anti-oxidants 25000-50000 IU, Vitamin E 100-400 units / day as an antioxidant. recommendation consumption of potassium, sodium and chloride respectively 45-145 meq / day, calcium 60 meq / day, magnesium 35 meq / day, and phosphate 23 mmol





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